Factoring by Substitution — Cheat sheet
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Key method
For x4+bx2+c, put u=x2. The expression becomes u2+bu+c. When solving over the reals, remember that u=x2≥0.
Example
Factor x4−5x2+4. With u=x2,
u2−5u+4=(u−1)(u−4).
Substitute back to get (x2−1)(x2−4), then factor both differences of squares:
(x−1)(x+1)(x−2)(x+2).
Avoid this mistake
Do not stop a solution at u=1,4 when the question asks for x. Each positive square value gives two real roots.